The Microsoft Office application error 0xc0000142 typically occurs because there’s an issue with the application’s startup process. It is often caused by corrupted files, missing updates, or issues with the registry. Here’s a step-by-step guide to fixing it:

1. Restart Your Computer

• Sometimes a simple restart can resolve temporary glitches causing the error.

2. Repair Microsoft Office

• Windows Settings:
  • Open Settings (Windows key + i) → Apps → Apps & features.
  • Find Microsoft Office in the list & Click on Advanced Options.
  • 
  • 
  • Click on Repair. (depends on the version).
  • 
  • Choose Quick Repair first. If the issue persists, try the Online Repair option.

3. Update Microsoft Office

• Through Office:
  • Open any Office app (e.g., Word or Excel).
  • Go to File → Account → Update Options.
  • 
  • 
  • 
  • Click Update Now and install any available updates.

4. Run Office in Safe Mode

• How to Start in Safe Mode:
  1. Press Windows + R, type the command for the app you want to open in Safe Mode:
     • Word: winword /safe
     • Excel: excel /safe
     • PowerPoint: powerpnt /safe
  2. If it works in Safe Mode, disable add-ins:
     • Go to File → Options → Add-ins.
     • Select COM Add-ins from the drop-down and click Go.
     • Uncheck all add-ins and restart the app.

5. Check for Windows Updates

• Install the Latest Windows Updates:
  1. Go to Settings → Update & Security → Windows Update.
  2. Click Check for Updates and install any pending updates.

6. Re-register DLL Files

• Sometimes, DLL files used by Office might be causing the issue.
  1. Open Command Prompt as Administrator:
     • Press Windows + S, type cmd, right-click, and choose Run as Administrator.
  2. Run the following command:
     • for %i in (%windir%\system32\*.dll) do regsvr32.exe /s %i
     • 

7. Perform an SFC and DISM Scan

• To fix corrupted system files:
  1. Open Command Prompt as Administrator.
  2. Run the following commands one at a time:
     • sfc /scannow DISM /Online /Cleanup-Image /RestoreHealth
     • 

8. Reinstall Microsoft Office

• If none of the above works:
  1. Uninstall Microsoft Office:
     • Open Settings → Apps → Installed apps.
     • Find Microsoft Office and uninstall it.
  2. Download the latest Office setup from Office.com.
  3. Reinstall the suite and activate it with your license.

9. Check for Third-Party Conflicts

• Some antivirus or third-party software may interfere with Office:
  • Temporarily disable antivirus software and try launching Office again.
  • If it works, add Office to your antivirus exceptions list.

If you’ve tried these steps and the issue persists, let me know where you’re stuck, and we can troubleshoot further! (Contact US)

Detailed video below: